Revivicor's Vision
To provide organs from gene-edited pigs to overcome the critical shortage of human organs for transplant.
There is a major shortage of organs for heart and kidney transplant.
Data based on United Therapeutics internal market research, the Health Resources & Services Administration and UNOS.
Xenotransplantation is a key solution.
Pigs can provide a plentiful and accessible supply of transplantable
organs.
History
1996
Revivicor (successor to PPL Therapeutics) collaborated with the Roslin Institute to establish the world’s first cloned mammal
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2000
Revivicor (successor of PPL Therapeutics) produced the world’s first cloned pigs
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2001
Revivicor (successor to PPL Therapeutics) established the world’s first alpha-gal knockout pigs, the GalSafe™ lineage progenitors. The GalSafe™ line has one gene inactivated and this line is free of the epitope galactose alpha-1-3 galactose (alpha-gal)
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Revivicor formed as a spin-out from PPL Therapeutics
2011
Revivicor acquired by United Therapeutics Corporation to create an unlimited supply of manufactured organs for transplantation
unither.com2020
Revivicor received a first-of-its-kind approval from the FDA for use of the GalSafe™ pig as a source of food for human consumption, and as a source of human therapeutics
Health and Safety Data FDA News Release2021
Revivicor's UKidney™ from a pig was transplanted into the body of a recently deceased human maintained on artificial support UKidney™ is a development-stage product not approved for sale in any jurisdiction
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A UHeart™ from a Revivicor pig was used clinically and established a new record for longest surviving recipient of a xenotransplantation productUHeart™ is a development-stage product not approved for sale in any jurisdiction
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